Nouveau procédé pour la production d'oxabispidines
| N° de brevet: |
EP1900741 (A1) |
| Date de publication: |
2008-03-19 |
| Inventeur(s): |
PAVEY JOHN [GB]; |
| Demandeur(s): |
ASTRAZENECA AB [SE]; |
| Classification: |
C07D498/08;A61K31/5386;A61P9/06;C07D245/02; |
| N° de demande: |
EP20070121849 20011001 |
| Numéro(s) de priorité: |
EP20010972866 20011001;PH20000002701 20001002;WO2000SE01994 20001013 |
There is provided a process for the preparation of a compound of formula I, (I), or a pharmaceutically acceptable derivative thereof, wherein A, B, G, R 1 , R 2 , R 3 , R 4 and R 41 to R 46 have meanings given in the description, which process comprises the dehydrative cyclisaton of a compound of formula II, (II).
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