Inhibiteurs de GPR87 pour le traitement de cancer- Brevets EP1900377 (A1)

Inhibiteurs de GPR87 pour le traitement de cancer

N° de brevet:	EP1900377 (A1)
Date de publication:	2008-03-19
Inventeur(s):	GLATT SEBASTIAN [AT];SOMMERGRUBER WOLFGANG [AT];HASLINGER CHRISTIAN [AT];STRATOWA CHRISTIAN [AT];GARIN-CHESA PILAR [AT];
Demandeur(s):	BOEHRINGER INGELHEIM INT [DE];
Classification:	A61K39/395;A61K39/00;A61K31/7088;A61K48/00;A61K51/10;A61K47/48;A61P35/00;C07K16/28;C07K16/00;C12N15/11;G01N33/53;G01N33/68;C07K19/00;
N° de demande:	EP20060120540 20060912
Numéro(s) de priorité:	EP20060120540 20060912

Use of GPR87 for the generation of GPR87 inhibitors. GPR87 inhibitors, e.g. anti-GPR87 antibodies and small molecules, are useful as drugs in the treatment of cancer. Methods for identifying small molecule GPR87 inhibitors employ cells transfected with GPR87 or GPR87-G-alpha fusion proteins.