COMPOSITION MEDICINALE DESTINEE A AMELIORER OU A TRAITER L'INTOLERANCE AU GLUCOSE, LE PRE–DIABETE, L'INSULINORESISTANCE ET L'HYPERINSULINEMIE ET CONTENANT UN AGENT HYPOGLYCEMIANT

N° de brevet: EP1891971 (A1)
Date de publication: 2008-02-27
Inventeur(s): KITAHARA YOSHIRO [JP];MIURA KYOKO [JP];
Demandeur(s): AJINOMOTO KK [JP];
Classification: A61K45/00;A61K31/4045;A61P3/10;A61P9/10;A61P43/00;C07D209/44;
N° de demande: EP20060712691 20060131 
Numéro(s) de priorité: WO2006JP301548 20060131;JP20050023289 20050131 
The present invention provides a pharmaceutical composition containing a hypoglycemic agent(s) as an active ingredient for improving or treating impaired glucose tolerance, borderline diabetes, insulin resistance or hyperinsulinemia. The present invention further provides a pharmaceutical composition for preventing or delaying the progression from impaired glucose tolerance, borderline diabetes, insulin resistance or hyperinsulinemia to diabetes mellitus or metabolic syndromes; or the progression to the state easy to develop macrovascular disorders, cardiovascular events or ischemic heart disease.

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