A hose (10) including at least one permeation resistant layer (12), an elastomeric layer (18) overlaying each at least one permeation resisting layer (12), at least one reinforcement layer (20) overlaying an elastomeric layer (18), and a cover layer (22) overlaying the at least one reinforcement layer (20), wherein the at least one permeation resistant layer (12) includes a plurality of sublayers of at least two different thermoplastics wherein the sublayers have a thickness of less than 2500 nanometers.